3-Amino-2-(methoxycarbonyl)-7-azabenzo[b]thiophene, 3-Amino-2-(methoxycarbonyl)thieno[2,3-b]pyridine - Names and Identifiers
Name | Methyl 3-Aminothieno[2,3-B]Pyridine-2-Carboxylate
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Synonyms | AKOS 93608 3-AMino-2-carboMethoxythieno[2,3-b]pyridine 2-(Methoxycarbonyl)thieno[2,3-b]pyridin-3-amine METHYL 3-AMINOTHIENO[2,3-B]PYRIDINE-2-CARBOXYLATE Methyl 3-Aminothieno[2,3-B]Pyridine-2-Carboxylate METHYL 3-AMINOTHIOPHENO[2,3-B]PYRIDINE-2-CARBOXYLATE Methyl 3-Aminothiopheno[2,3-B]Pyridine-2-Carboxylate 3-AMino-thieno[2,3-b]pyridin-2-carboxylic acid Methyl ester Thieno[2,3-B]Pyridine-2-Carboxylic Acid, 3-Amino-, Methyl Ester Thieno[2,3-b]pyridine-2-carboxylic acid, 3-amino-, methyl ester (9CI) 3-Amino-2-(methoxycarbonyl)-7-azabenzo[b]thiophene, 3-Amino-2-(methoxycarbonyl)thieno[2,3-b]pyridine
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CAS | 111042-89-8
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InChI | InChI=1/C9H8N2O2S/c1-13-9(12)7-6(10)5-3-2-4-11-8(5)14-7/h2-4H,10H2,1H3 |
3-Amino-2-(methoxycarbonyl)-7-azabenzo[b]thiophene, 3-Amino-2-(methoxycarbonyl)thieno[2,3-b]pyridine - Physico-chemical Properties
Molecular Formula | C9H8N2O2S
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Molar Mass | 208.24 |
Density | 1.422±0.06 g/cm3(Predicted) |
Melting Point | 198-200°C |
Boling Point | 377.6±37.0 °C(Predicted) |
Flash Point | 182.1°C |
Vapor Presure | 6.69E-06mmHg at 25°C |
pKa | 4.96±0.40(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.699 |
3-Amino-2-(methoxycarbonyl)-7-azabenzo[b]thiophene, 3-Amino-2-(methoxycarbonyl)thieno[2,3-b]pyridine - Risk and Safety
Hazard Symbols | Xi - Irritant
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Hazard Class | IRRITANT |
3-Amino-2-(methoxycarbonyl)-7-azabenzo[b]thiophene, 3-Amino-2-(methoxycarbonyl)thieno[2,3-b]pyridine - Introduction
Methyl 3-aminopyridylthiophene-2-carboxylate is an organic compound with the chemical formula C10H10N2SO2; it is an organic acid methyl ester with aromatic properties.
The main properties of 3-aminopyridine thiophene-2-carboxylic acid methyl ester include:
1. Appearance and state: colorless to light yellow crystal;
2. melting point: about 120-124 degrees Celsius;
3. solubility: soluble in some organic solvents such as toluene and dichloromethane, insoluble in water.
3-aminopyridine thiophene-2-carboxylic acid methyl ester has certain application value in the field of medicine:
1. It can be used as a synthetic intermediate for drug synthesis in the pharmaceutical field;
2. As an organic synthesis reagent, a catalyst for organic chemical reactions.
The preparation method of 3-aminopyridine thiophene-2-carboxylic acid methyl ester can be carried out by the following steps:
1. dissolving 3-aminopyridine thiophene-2-acid in an appropriate amount of organic solvent;
2. Add an appropriate amount of methanol to it;
3. carry out esterification reaction under appropriate reaction conditions;
4. The precipitate was filtered and the product was washed and dried.
Regarding safety information, 3-aminopyridine thiophene-2-carboxylic acid methyl ester may corrode in humid environments. During use, contact with skin, eyes and respiratory tract should be avoided. Protective gloves, goggles and masks must be worn during operation. Operate in a well-ventilated area and away from fire and high temperature conditions. In case of contact, flush immediately with plenty of water and seek medical attention.
Last Update:2024-04-09 20:02:46